Informatics Publishing Limited

S. Bindu , C. R. Chitra , C. Anilkumar

Abstract

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S. Grover ¹, A. Chhabra ¹, S. Bindu ²

Affiliations
1 Punjab Institute of Medical Sciences Jalandhar, Punjab, IN
2 Shri MP Shah Medical College Jamnagar, Gujarat, IN

Abstract

Background:Menorrhagia accounts for 12% of all gynaecology consultations and is one of the most common causes of iron deficiency anaemia in females after nutritional anaemia.

Objectives: To evaluate the efficacy and side effects of ormeloxifene in cases of dysfunctional uterine bleeding.

Material and Methods: 30 women aged 28-46 years who attended the outpatient gynaecology department in a tertiary care hospital with complaint of heavy menstrual flow were recruited for the study. Two pretreatment baseline cycles were compared to the treatment cycles of ormeloxifene. The main outcomes measured were menstrual blood, blood haemoglobin levels and endometrial thickness in proliferative phase as studied by TVS. Data thus collected was compared and analysed statistically.

Results: Total number of bleeding days per year decreased by 76%. Total no. of pads soiled per cycle decreased by 76.3%. All the patients reported disappearance of clots, 66.66% within 1 month of the treatment only. Dysmenorrhoea was relieved in 62.5% patients. Mean increase in Hb was 0.42g%.

Conclusion: Ormeloxifene is very effective in improving all the parameters of blood loss in DUB including the no. of days of bleeding, no. of pads soiled and the passage of clots. Ormeloxifene has a good patient acceptability and compliance due to its minimal side effects, low cost and simple dosage schedule. In the peri-menopausal age group, drug is protective against breast malignancy and osteoporosis. Ormeloxifene has the potential to be an effective treatment for DUB and should always be considered amongst the treatment options.

Keywords

Dysfunctional Uterine Bleeding, Menorrhagia, Ormeloxifene.

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S. Rekha ¹, L. Valeria ¹, S. Bindu ¹, K. Nandana ¹

Affiliations
1 Birsa Agricultural University, Ranchi - 6, IN

Abstract

Jharkhand is one of the Eastern States of India, where large concentration of tribals are found. The state although very rich in mineral and natural resources, is one of the poorest states in the country in terms of human development. It has been termed as food insecure region with around 61 per cent of the rural population below poverty line. Ranchi is the most populous district of the state, having about 9.6 lakh tribals forming 43.56 per cent of its total population.

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